Sustainability at Santen

Based on Santen's Core Principle "Tenki ni sanyo suru," Santen not only contributes to the sustainable development of society but also aims to achieve its own sustainable growth.

Sustainability Policy

Based on Santen's Core Principle: "Tenki ni sanyo suru," Santen not only contributes to the sustainable development of society but also aims to improve corporate value over the medium to long term.

Sustainability Promotion System

Santen holds a Sustainability Committee, chaired by the CEO and composed of executive officers from related divisions. The Global Head of Sustainability (executive officer) oversees company-wide sustainability activities.

The committee meets at least twice a year, discussing and determining Group-wide policies and targets for sustainability promotion activities. These targets are based on the Core Principle, sustainability policy, Group strategies, and social issues that include human rights, labor, environment, and anti-corruption.

We communicate decisions and other information through the executive management of each department. Matters related to Group management strategies are proposed to the Executive Committee for approval, and important matters are referred to the Board of Directors.

Santen's Materiality

Santen identifies and engages with materialities.

Materiality ( Most Important Materiality)Definition
Generating Products and Services Contributing to Eye HealthProvide solutions to unmet needs, including rare diseases, through product development and service creation
Ensuring Product Quality and Stable SupplyEnsure the continuous supply of products with guaranteed quality and safety in the necessary quantities in a timely manner and establish a system for emergencies
Penetration of Products and Market CreationBecome a trusted partner and maximize the value provided to patients and customers, contributing to the realization of optimal healthcare, including patient access
Enhancing the Value of Working at Santen and Strengthening People/OrganizationPromote the philosophy framework that Santen contributes to ophthalmic healthcare and maximize the capabilities of people and organizations that can put it into practice
Business Operations with High Ethical StandardsIn all aspects of our business, we conduct corporate activities based on a high level of ethics that goes beyond mere compliance with laws and regulations
Transparent Disclosure of InformationWith high level of transparency, we disclose the information that stakeholders need in a timely and appropriate manner
Promoting DE&I (*)Enhance creativity and promote value creation through mutual respect among diverse talents
Respect for Human RightsUnderstand human rights issues and conduct activities that respect human rights throughout the entire value chain
Sustainable ProcurementReduce procurement risks through sustainable sourcing and appropriate supplier management
Ensuring Information SecurityThe domain of protecting company’s valuable assets and data from unauthorized access, disclosure, alteration, and destruction and ensuring the confidentiality, integrity, and availability of information
Promoting Digital TransformationContribute to operational efficiency, business growth, and opportunity creation through the utilization of digital technology
Measures against Climate ChangeImplement climate change mitigation and adaptation measures for business continuity, and reduce energy consumption and greenhouse gas emissions
Environmental Load ReductionMinimize environmental impact, including resource use, pollution, and effects on biodiversity, across all business activities
  • Diversity Equity & Inclusion

Process for Identifying Materiality

May 2025, in terms of formulating the Medium-Term Management Plan, we reviewed our materiality.

Step 1: Extraction of Issues and Risk/Opportunity Analysis

Broadly list social issues and, in addition to company-wide risk items, conduct risk and opportunity analysis for each relevant department

Step 2: Organize and Integrate Items, Define as Materiality

Narrow down to 13 items based on the direction of the Medium-Term Management Plan and various guidelines

Step 3: Evaluation of Financial Impact

Estimate the financial impact based on the degree of impact on profits and frequency of occurrence and evaluate the impact

Step 4: Identification of Most Important Materiality

Identify the four items with the greatest financial impact as the most important materiality

Step 5: Dialogue with External Stakeholders and Experts

Evaluate the validity though dialogue with external stakeholders and experts

Step 6: Setting Strategies, Indicators, and Goals

Formulate strategies, indicators, and goals to address risks and opportunities, approved by the Board of Directors

Strategies for Most Important Materialities

Generating Products and Services Contributing to Eye Health

We plan to provide solutions to unmet needs, including rare diseases, through product development and service creation.

Risk Scenario

  • Exhaustion of the research development pipeline 【Mid-term/Long-term】
  • Increasing complexity of research development and intensified competition, resulting in a decline in the generation of new products【Short-term/Mid-term/Long-term】

Opportunity Scenario

  • Identification of unmet needs and creation of unique and valuable therapeutic solutions 【Mid-term/Long-term】
  • Promotion of joint research, development, and ecosystem 【Short-term/Mid-term/Long-term】

Countermeasures

  • Identification of therapeutic solutions in the field of ophthalmic diseases where strengths can be leveraged
  • Active evaluation and introduction of therapeutic candidate compounds, advancement of collaborative research and development, utilization of ecosystems, and investment in research and development of new modalities
  • Development of ophthalmic formulations and application in the field of ophthalmic diseases that are unattainable by other competitors

Impact

  • Contributing to the treatment of patients in the field of eye diseases where there were no therapeutic drugs until now
  • Contributing to patient care by creating products that address unmet needs of existing products (e.g., reducing the burden of eye drop administration)
  • Continuing and developing business with partner companies

Ensuring Product Quality and Stable Supply

We will ensure the continuous supply of products that meet quality and safety standards in the required quantities and in a timely manner, while also establishing a system to respond to emergencies.

Risk Scenario

  • Decreasing supply capacity and delayed recovery during natural disasters, etc. 【Short-term/Mid-term/Long-term】
  • Delays in product supply due to the burden of complying with increasingly advanced GMP(*) standards and other regulations【Short-term/Mid-term/Long-term】
  • Increased volatility, uncertainty, complexity, and ambiguity (VUCA) in the market, leading to higher difficulty in production capacity and supply planning【Short-term/Mid-term】
  • Abbreviation of “Good Manufacturing Practice.” Standards for manufacturing and quality control of pharmaceuticals and quasi-drugs.

Opportunity

  • Establishing a global product supply network that is resilient to diverse environmental changes, including regulatory aspects 【Mid-term/Long-term】

Countermeasures

  • Optimization of production volume balance between sites, appropriate inventory level management, and advance preparation of alternative production sites for each product
  • Continuous improvement of quality systems
  • Strategic collaboration with contract manufacturing organizations
  • Optimization of the production and supply network, including in-house production and contract manufacturing

Impact

  • Ensuring the stable supply of high-quality products that comply with regulations, thereby providing patients with continuous treatment options and enhancing customer trust in Santen
  • Maintaining production and supply capabilities resilient to environmental changes

Penetration of Products and Market Creation

We aim to become a trusted partner and maximize the value provided to patients and customers, contributing to the realization of optimal healthcare, including patient access.  

Risk Scenario

  • Intensified price competition for long-listed products due to drug price suppression and the promotion of generic drug use【Short-term/Mid-term/Long-term】
  • Excessive dependence on sales revenue from the Japanese market, which is experiencing a slowdown in growth 【Short-term/Mid-term】

Opportunity

  • Expansion of the global ophthalmology market 【Mid-term/Long-term】
  • Exploration of potential markets driven by unmet needs in ophthalmology 【Short-term/Mid-term】

Countermeasures

  • Enhancing organizational capabilities to disseminate correct treatment concepts and make appropriate treatment proposals, thereby maximizing and maintaining product value
  • Strengthening presence in EMEA(*), Asia, and China
  • Identifying unmet treatment needs and exploring areas that enable the provision of new value
  • Europe, the Middle East and Africa

Impact

  • Providing optimal ophthalmic care to a greater number of patients
  • Alleviating eye-related concerns and anxieties by offering new treatment options

Enhancing the Value of Working at Santen and Strengthening People/Organization

We will promote the Santen’s philosophy framework for contributing to ophthalmic care and maximize the capabilities of people and organization capacity to put this philosophy into practice.

Risk Scenario

  • Cost pressures and difficulties in securing talent due to rising global labor costs 【Short-term/Mid-term/Long-term】
  • Decline in organization performance due to lack of flexible systems and structures 【Short-term/Mid-term】
  • Risk of talent attrition and loss of acquisition opportunities due to the inability to clarify the value of working at Santen amidst increasing diversity in values and higher talent mobility 【Mid-term/Long-term】

Opportunity

  • Enhancing individual growth rates and organization productivity by providing numerous experiences and challenges through flexible systems and structures 【Short-term/Mid-term/Long-term】
  • Clarifying the value of working within the Santen to attract and retain talented individuals who resonate with that value【Short-term/Mid-term/Long-term】

Countermeasures

  • Implementation and promotion of company-wide cross-functional projects and strategic internal dual programs
  • Enhancing employee performance and engagement through the dissemination of Santen’s Core Principle, Guiding Principle, and Values
  • In addition to activities promoting the Core Principle, Guiding Principle, and Values, communicating the significance of working at Santen, to the outside world through the expansion of systems that accommodate diverse working styles and fair evaluation and compensation systems

Impact

  • Achieving high performance through an organization and employees who embody the Core Principle, Guiding Principle, and Values of Santen, thereby strengthening competitiveness, further developing the business, and providing new value to society.

Indicators and Targets

We are setting indicators and targets for each materiality and actively promoting our initiatives.

Materiality ( Most Important Materiality)Indicators and Targets
Generating Products and Services Contributing to Eye Health
  • Development of products (therapeutic areas/regions) based on plans to address unmet medical needs
Ensuring Product Quality and Stable Supply
  • On Time – In Full: OTIF (% of orders shipped on-time and in-full)
Penetration of Products and Market Creation
  • Improvement in contribution to global patients (market share)
  • Total number of contributing patients in newly created markets (Myopia and Ptosis Rx(*1) market)
Enhancing the Value of Working at Santen and Strengthening People/Organization
  • Adoption of the new philosophy framework (Core Principle, Vision, Guiding Principle, and Values)
  • Improvement of the global engagement score
Business Operations with High Ethical Standards
  • Annual compliance education attendance rate: 95% or more
  • Major compliance violations: 0
Transparent Disclosure of Information
  • Implementation of statutory and timely disclosure based on various laws and regulations, and timely and voluntary disclosure to external stakeholders (e.g., integrated reports)
Promoting DE&I
  • Continue to promote diversity in senior management
  • Continuously increase the ratio of female managers (domestic)
Respect for Human Rights
  • Establish internal and external human rights due diligence processes and structures
Sustainable Procurement
  • Supplier evaluation rate: 85% or higher
  • Supplier training rate: 80% or higher
  • ESG educational attendance rate in purchasing departments: 100%
Ensuring Information Security
  • Percentage of critical classified security incidents resolved within the scope of SLA and OLA(*2)
  • Cybersecurity training completion rate
Promoting Digital Transformation
  • Percentage of DX-related projects (e.g., ERP, generative AI) that achieved the initially expected effects: 80% or more
Measures against Climate Change
  • Reduce CO2 emissions by 2030 against the 2019 level as follows
    ‐Scope 1 and 2: 50% reduction
    ‐Scope 3 Category 1 (non-consolidated): 15% reduction
Environmental Load Reduction
  • [Water Resources]: Intake of water per unit of production: 12.4m3/10,000 or less
  • [Resource Conservation]: Recycling rate: 98% or more
  • [Plastic]:
    1) 60% of plastic eye drop containers being produced from biomass plastic in 2030
    2) Reduce plastic materials used in packaging and packing materials by 15% by 2030 compared to 2019
  1. Prescription pharmaceuticals
  2. SLA: “Service Level Agreement”, OLA: “Operational Level Agreement”.

Integration of non-financial metrics into the compensation

Some non-financial indicators are incorporated into the compensation for executives and employees. For example, the following goals have been set for FY2025 and incorporated into the compensation.

Strategic objectives pertaining to the Performance Share Unit System for executives

  • Realization of a market-creating-type growth model in the areas of myopia and blepharoptosis
  • Establishment of a leadership position in overseas market
  • Innovation towards a high- value Rx portfolio
  • Sustainable optimization of stable supply and costs
  • Enhancement of the value of working at Santen and strengthening the capabilities of people and the organization

Themes of Non-Financial Multiplier targets for employees

  • Further promote our new Guiding Principle and Values and improve engagement among employees through participation in People Pulse Surveys (*)
  • Intensify employees’ understanding of online security by conducting information security and e-mail security training courses
  • Strengthen global risk management, increase employees’ compliance awareness, and improve the company’s self-regulation and transparency by achieving high attendance rates in compliance-related e-learning programs
  • People Pulse Surveys: Questionnaires that are repeated over a short period of time to ascertain the status of employees